AK-1690 is a selective PROTAC degrader targeting STAT6(DC50=1 nM) with a Ki of 6 nM against human STAT6. AK-1690 degrades STAT6 via the interaction of STAT6 with cereblon and a ubiquitin-like process. AK-1690 effectively depletes STAT6 protein in mouse liver and lung tissues, and is applicable to research related to leukemia, Hodgkins lymphoma, follicular lymphoma, etc.[1].
Molekulargewicht:
1016.05
Reinheit:
99.91
CAS Nummer:
[2984505-88-4]
Formel:
C51H56F2N5O11PS
Target-Kategorie:
PROTACs,STAT
Anwendungsbeschreibung:
MCE Product type: Reference compound
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