Mavatrep-d6 (JNJ-39439335-d6) is a deuterated labeled Mavatrep (HY-16935). Mavatrep (JNJ-39439335) is an orally active, selective and potent TRPV1 antagonist with high affinity for hTRPV1 channels (Ki=6.5 nM). Mavatrep antagonizes capsaicin-induced Ca2+ influx with an IC50 value of 4.6 nM. Mavatrep can be used in some studies of neuropathic pain[1].
Molekulargewicht:
428.48
Formel:
C25H15D6F3N2O
Target-Kategorie:
Isotope-Labeled Compounds,TRP Channel
Anwendungsbeschreibung:
Isotope-Labeled Compounds
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