YT 6-2 is the p62/SQSTM1 targeting, autophagy-targeting ligand (ATL) of AUTOTAC ATC-324 (HY-169385), which is an bivalent AR (Androgen Receptor) degrader. ATC-324 can reduce nuclear AR levels and downregulate target gene expression of AR and AR-v7, and also has a degradation effect on common AR mutants in PCa[1].
Molekulargewicht:
459.48
CAS Nummer:
[2409959-90-4]
Formel:
C25H27F2NO5
Target-Kategorie:
AUTACs
Anwendungsbeschreibung:
Reference compound
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