Lipid N2-3L, CAS [[2924606-55-1]] Preis auf Anfrage
Artikelnummer:
MCE-HY-169478
Hersteller Artikelnummer:
HY-169478
Alternativnummer:
MCE-HY-169478-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Lipid N2-3L is an ionizable cationic lipid (pKa = 8.99) that can be used to generate supramolecular lipid nanoparticles (SMLNPs) for mRNA delivery. Lipid nanoparticles formed by encapsulating a luciferase reporter gene with Lipid N2-3L were detected to accumulate in the lymph nodes of mice, indicating that they can effectively enter the mouse immune system. Lipid nanoparticles formed by encapsulating ovalbumin mRNA and the TLR7/8 agonist Resiquimod (HY-13740) with Lipid N2-3L were able to reduce tumor volume and increase survival in the MC-38-OVA mouse colon cancer model. Lipid N2-3L can be used in the research of drug delivery for cancer-related therapies[1].
Molekulargewicht:
840.27
CAS Nummer:
[2924606-55-1]
Formel:
C48H93N3O8
Target-Kategorie:
Liposome
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
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