Sitravatinib, CAS [[1123837-84-2]]
Artikelnummer:
MCE-HY-16961
| Artikelname: |
Sitravatinib, CAS [[1123837-84-2]] |
| Artikelnummer: |
MCE-HY-16961 |
| Hersteller Artikelnummer: |
HY-16961 |
| Alternativnummer: |
MCE-HY-16961-100MG,MCE-HY-16961-25MG,MCE-HY-16961-5MG,MCE-HY-16961-50MG,MCE-HY-16961-10MMX1ML,MCE-HY-16961-200MG,MCE-HY-16961-10MG |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| Alternative Synonym: |
MGCD516, MG-516 |
| Sitravatinib (MGCD516) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively[1]. Sitravatinib shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment[2]. |
| Molekulargewicht: |
629.68 |
| Reinheit: |
99.57 |
| CAS Nummer: |
[1123837-84-2] |
| Formel: |
C33H29F2N5O4S |
| Target-Kategorie: |
c-Kit,Discoidin Domain Receptor,FLT3,Trk Receptor,VEGFR |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
