LDHA-IN-1 (Compound 1j) is a selective, competitive LDH-A inhibitor, with Ki values of 8.9 µM (NADH assay) and 4.7 µM (Pyruvate assay) against hLDH-A. LDHA-IN-1 inhibits cancer cell proliferation under hypoxic conditions. LDHA-IN-1 can be used in the research of ovarian cancer, colorectal cancer, mesothelioma and pancreatic cancer[1].
Molekulargewicht:
321.26
CAS Nummer:
[1269802-68-7]
Formel:
C16H10F3NO3
Target-Kategorie:
Lactate Dehydrogenase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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