Darolutamide-d4, CAS [[2484757-20-0]]

Produktübersicht

• Artikelname: Darolutamide-d4, CAS [[2484757-20-0]]
• Artikelnummer: MCE-HY-16985S
• Hersteller Artikelnummer: HY-16985S
• Alternativnummer: MCE-HY-16985S-1MG,MCE-HY-16985S-10MG,MCE-HY-16985S-5MG,MCE-HY-16985S-10MMX1ML,MCE-HY-16985S-500UG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: ODM-201-d4, BAY-1841788-d4

Produktbeschreibung

Darolutamide-d4 (ODM-201-d4) is deuterium labeled Darolutamide (HY-16985). Darolutamide (ODM-201) is an orally active competitive androgen receptor (AR) antagonist, with a Ki of 11 nM for rat wild-type AR (wtAR) and an IC50 of 26 nM for human wild-type AR (hAR)-mediated transcriptional activation[1]. Darolutamide inhibits testosterone-induced AR nuclear translocation and transcriptional activation[1]. Darolutamide exerts selective effects on AR-positive cells by inhibiting AR-dependent signaling pathways, and its active metabolite retains full antagonistic activity against AR mutants[1]. Darolutamide can be used for the research of prostate cancer, including androgen receptor-dependent prostate cancer[1].

Produkteigenschaften

• Molekulargewicht: 402.87
• Reinheit: 98.58
• CAS Nummer: [2484757-20-0]
• Formel: C19H15D4ClN6O2
• Target-Kategorie: Androgen Receptor,Isotope-Labeled Compounds

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Isotope-Labeled Compounds