BCRP-IN-2 has BCRP inhibitory activity and shows even greater inhibition of BCRP after activation by ultraviolet light. BCRP-IN-2 can be a valuable probe for studying the interactions of quinazolinamine derivatives with BCRP, as it stimulates ATP hydrolysis of the BCRP transport protein, increasing the accumulation of mitoxantrone (HY-13502) in H460/MX20 cells with BCRP overexpression[1].
Molekulargewicht:
339.35
CAS Nummer:
[2953730-35-1]
Formel:
C19H13N7
Target-Kategorie:
BCRP
Anwendungsbeschreibung:
MCE Product type: Reference compound
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