GlcCer (d18:1/18:0) (C18 Glucosyl(beta) ceramide (d18:1/18:0)) is a glycosphingolipids that activates the Wnt/beta-catenin pathway by targeting LRP6. GlcCer (d18:1/18:0) drives EMT, migration, invasion and GBA1-mediated liver cancer metastasis. GlcCer (d18:1/18:0) accumulates to impair lysosomal function and induce toxic alpha-synuclein aggregation. GlcCer (d18:1/18:0) supports growth, sporulation, germination and virulence in Penicillium digitatum. GlcCer (d18:1/18:0) is reduced in demyelinated mouse corpus callosum. GlcCer (d18:1/18:0) can be used for the research of liver cancer, synucleinopathies, fungal, Parkinsons disease and Gaucher disease[1][2][3][4][5].
Molekulargewicht:
728.09
Reinheit:
99.93
CAS Nummer:
[95119-86-1]
Formel:
C42H81NO8
Target-Kategorie:
Fungal,Wnt,beta-catenin
Anwendungsbeschreibung:
MCE Product type: Natural Products
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