Dapitant (RPR 100893) is a non-peptide Substance P antagonist with high affinity for the human NK1 receptor. It belongs to the 7,7,4-trimethylperhydroisoindole class of compounds. Dapitant inhibits the binding of Substance P to NK1 receptors, thereby blocking its neurokinin-mediated effects. This novel antagonist represents a potential therapeutic option for conditions involving Substance P, such as neurogenic inflammation and pain modulation[1].
Molekulargewicht:
561.71
CAS Nummer:
[153438-49-4]
Formel:
C37H39NO4
Target-Kategorie:
Neurokinin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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