ISM012-042, CAS [[2924181-80-4]]

Produktübersicht

• Artikelname: ISM012-042, CAS [[2924181-80-4]]
• Artikelnummer: MCE-HY-170522
• Hersteller Artikelnummer: HY-170522
• Alternativnummer: MCE-HY-170522-10MMX1ML,MCE-HY-170522-100MG,MCE-HY-170522-50MG,MCE-HY-170522-25MG,MCE-HY-170522-10MG,MCE-HY-170522-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

ISM012-042 is an orally active, selective inhibitor of PHD1 and PHD2, with IC50 values of 1.9 nM and 2.5 nM, respectively. ISM012-042 stabilizes HIF1alpha protein in intestinal epithelial cells, thereby activating gene transcription programs associated with mucus production, tight junction formation, anti-inflammatory mediator generation and wound healing, which fundamentally promotes mucosal barrier repair and regulates intestinal immunity. ISM012-042 can be used for the research of inflammatory bowel disease[1].

Produkteigenschaften

• Molekulargewicht: 489.53
• Reinheit: 98.69
• CAS Nummer: [2924181-80-4]
• Formel: C25H27N7O4
• Target-Kategorie: HIF/HIF Prolyl-Hydroxylase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound