PPARgamma/delta modulator 2 (Compound 3h) is a PPARgamma agonist and PPARdelta antagonist. The Ki values for PPARgamma and PPARdelta are 2.8 µM and 43 nM, respectively. PPARgamma/delta modulator 2 significantly enhances the production of Adiponectin and promotes adipogenic differentiation of human bone marrow mesenchymal stem cells (hBM-MSCs). PPARgamma/delta modulator 2 can be used in the study of metabolic disorders associated with hypoadiponectinemia[1].
Molekulargewicht:
564.67
Formel:
C17H17ClIN5O2Se
Target-Kategorie:
PPAR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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