HP211206 is a SARS-CoV-2 main protease (Mpro) PROTAC degrader. HP211206 effectively degrades SARS-CoV-2 Mpro and its drug-resistant mutants. HP211206 has an IC50 of 181.9 nM and a DC50 of 621 nM for Mpro. HP211206 has antiviral activity. (Pink: H117 (HY-170599), Black: linker (HY-B0236), Blue: E3 ligase ligand (HY-41547))[1].
Molekulargewicht:
883.94
Reinheit:
99.94
Formel:
C42H55F2N9O10
Target-Kategorie:
PROTACs,SARS-CoV,Virus Protease
Anwendungsbeschreibung:
MCE Product type: Reference compound
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