JH-FK-08 is an inhibitor for the serine/threonine-specific phosphatase calcineurin. JH-FK-08 exhibits antifungal activity that inhibits C. neoformans with MIC80 of 0.8 µg/mL. JH-FK-08 exhibits immunosuppressive activity and inhibits the IL-2 expression with an IC50 of 42.6 nM. JH-FK-08 exhibits anti-infectious activity in mouse models[1].
Molekulargewicht:
864.07
CAS Nummer:
[3062848-75-0]
Formel:
C45H73N3O13
Target-Kategorie:
Fungal,Interleukin Related
Anwendungsbeschreibung:
MCE Product type: Reference compound
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