DOTA-NI-FAPI-04, CAS [[3078291-78-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: DOTA-NI-FAPI-04, CAS [[3078291-78-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-170779
• Hersteller Artikelnummer: HY-170779
• Alternativnummer: MCE-HY-170779-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

DOTA-NI-FAPI-04 is a FAP inhibitor (IC50 = 7.44 nM). By integrating FAP targeting with hypoxia-sensitive groups (nitroimidazole), DOTA-NI-FAPI-04 significantly enhances tumor uptake and retention capabilities. DOTA-NI-FAPI-04 chelates metallic isotopes (such as 68Ga and 177Lu) through DOTA to produce radioactive probes ([68Ga]Ga/DOTA-NI-FAPI-04 and [177Lu]Lu/DOTA-NI-FAPI-04), which can be used for research in tumor diagnostics and therapeutic agents. DOTA-NI-FAPI-04 holds dual targeting potential in the fields of cancer imaging, tumor microenvironment analysis, and radionuclide therapy, particularly suitable for scenarios where the tumor stroma and hypoxic regions synergistically interact[1].

Produkteigenschaften

• Molekulargewicht: 1154.18
• CAS Nummer: [3078291-78-5]
• Formel: C51H69F2N15O14
• Target-Kategorie: FAP

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1