KIT/PDGFRA-IN-1 Preis auf Anfrage
Artikelnummer:
MCE-HY-170911
| Artikelname: |
KIT/PDGFRA-IN-1 Preis auf Anfrage |
| Artikelnummer: |
MCE-HY-170911 |
| Hersteller Artikelnummer: |
HY-170911 |
| Alternativnummer: |
MCE-HY-170911-1UNIT |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| KIT/PDGFRA-IN-1 (compound 19) is a stem cell growth factor receptor (KIT) and platelet-derived growth factor receptor alpha (PDGFRA) inhibitor. KIT/PDGFRA-IN-1 inhibits KIT-wt, KIT-D816H, KIT-T670I, PDGFRA-wt, PDGFRA-D842V, PDGFRA-T674I and PDGFRA-G680R with IC50s of 2.3, 12, 492, 0.8, 99.9, 42.3, and 4.3 µM, respectively. KIT/PDGFRA-IN-1 inhibits GIST-T1, T1-a-D842V and GIST-48B cells (PDGFR- and KIT-Mutant GIST cell Lines) with GR50s of 12, 8900, 10 000 nM, respectively[1]. |
| Molekulargewicht: |
489.45 |
| Formel: |
C26H18F3N5O2 |
| Target-Kategorie: |
PDGFR |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound1 |
