NYY-6a is a Ferroptosis inhibitor. NYY-6a shows significant inhibitory activity against RSL3-induced ferroptosis across 786-O and HT-1080 cells with EC50s of 52 and 50 nM, respectively. NYY-6a functions as a radical trapping antioxidant (RTA) with efficacy of diminishing lipid peroxidation comparable to ferrostatin-1 and liproxtatin-1. NYY-6a is potential for ferroptosis related pathologies reasearch[1].
Molekulargewicht:
374.43
Formel:
C23H22N2O3
Target-Kategorie:
Ferroptosis
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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