Clonixeril (NSC 335504) is a non-nucleotide hSTING modulator. Clonixeril has weak agonist activity at micromolar concentrations and results in antagonism of the hSTINGWT pathway at low femtomolar (10-15 M) and in some cases even attomolar (10-18 M) concentrations. Clonixeril reduces hSTING oligomerization at a concentration of 1 aM-1 pM[1].
Molekulargewicht:
336.77
CAS Nummer:
[21829-22-1]
Formel:
C16H17ClN2O4
Target-Kategorie:
STING
Anwendungsbeschreibung:
MCE Product type: Reference compound
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