dAurAB5

Produktübersicht

• Artikelname: dAurAB5
• Artikelnummer: MCE-HY-171770
• Hersteller Artikelnummer: HY-171770
• Alternativnummer: MCE-HY-171770-25MG,MCE-HY-171770-10MG,MCE-HY-171770-1MG,MCE-HY-171770-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

dAurAB5 is a dual Aurora-A (DC50 = 8.8 nM) and Aurora-B (DC50 = 6.1 nM) PROTAC degrader. dAurAB5 induces degradation of Aurora-A and Aurora-B, reduces N-Myc levels, and decreases viability in IMR32 neuroblastoma cells. dAurAB5 downregulates the levels of AAK1, PTK2, GAK, and TTK. dAurAB5 can be used to study cancers such as neuroblastoma. (Pink: TTK ligand 2: HY-168542, Blue: Thalidomide-O-COOH: HY-103597, Black: 6-Aminocaproic acid: HY-B0236)[1].

Produkteigenschaften

• Molekulargewicht: 819.91
• Reinheit: 99.03
• Formel: C42H49N11O7
• Target-Kategorie: AAK1,Aurora Kinase,Cyclin G-associated Kinase (GAK),FAK,Mps1,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound