TC-2559 (free base), CAS [[189274-78-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: TC-2559 (free base), CAS [[189274-78-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-171807
• Hersteller Artikelnummer: HY-171807
• Alternativnummer: MCE-HY-171807-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

TC-2559 free base is a alpha4beta2 nicotinic acetylcholine receptor (nAChR) agonists with an EC50 of 0.18 µM. TC-2559 free base shows much weaker potencies on the group of b4-containing nAChR subtypes, alpha2beta4, alpha4beta4 and alpha3beta4 receptors, with EC50s in the range of 10-30 µM. TC-2559 free base can increase the discharge of dopamine cells in the ventral tegmental area (VTA) of rats in vitro, enhancing the excitability and aggressive behavior of VTA dopamine neurons. TC-2559 free base inhibits STAT3 to exert anti-inflammatory properties and relieves mice mechanical allodynia and improve rats cognitive deficits. TC-2559 free base can be used for the study of nerve pain[1][2][3][4][5].

Produkteigenschaften

• Molekulargewicht: 206.28
• CAS Nummer: [189274-78-0]
• Formel: C12H18N2O
• Target-Kategorie: nAChR,STAT

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound