12-Nitrolinoleate, CAS [[774603-05-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: 12-Nitrolinoleate, CAS [[774603-05-3]] Preis auf Anfrage
• Artikelnummer: MCE-HY-171895
• Hersteller Artikelnummer: HY-171895
• Alternativnummer: MCE-HY-171895-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 12-Nitro-9-cis,12-cis-octadecadienoic acid

Produktbeschreibung

12-Nitrolinoleate (12-Nitro-9-cis,12-cis-octadecadienoic acid) is an activator for peroxisome proliferator-activated receptor gamma (PPARgamma). 12-Nitrolinoleate is a nitrated form of linoleic acid. 12-Nitrolinoleate can be formed upon exposure to acidified nitrate and found in human red blood cells and plasma. 12-Nitrolinoleate can activate PPARgamma-dependent gene expression in MCF-7 cells expressing PPARgamma with an EC50 = 0.045 µM. 12-Nitrolinoleate is able to inhibit LPS (HY-D1056)-induced NF-kappaB transcription in RAW 264.7 cells. 12-Nitrolinoleate can inhibit IL-6, TNF-alpha and CCL2 induced by LPS[1][2][3].

Produkteigenschaften

• Molekulargewicht: 325.44
• CAS Nummer: [774603-05-3]
• Formel: C18H31NO4
• Target-Kategorie: Interleukin Related,NF-kappaB,PPAR,TNF Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound