MASP-2-IN-1 (Compound 77) is the inhibitor for mannan-binding lectin-associated serine protease (MASP), that inhibits MASP2 and MASP3 with IC50 of 11.4 nM and 13.2 µM. MASP-2-IN-1 exhibits a weak inhibitory activity against hERG with an IC50 of 175 µM. MASP-2-IN-1 reveals a poor stability in mouse plasma with a half-life of 4.4 hours[1].
Molekulargewicht:
463.51
Formel:
C22H21N7O3S
Target-Kategorie:
Potassium Channel,Ser/Thr Protease
Anwendungsbeschreibung:
MCE Product type: Reference compound
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