HYS-072 is an orally active derivative of chrysin (HY-14589) with antitumor activity. HYS-072 induces apoptosis and autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway and suppresses tumor growth in vivo in xenograft models by modulating autophagy-related pathways. HYS-072 can be used in the research of triple-negative breast cancer[1].
Molekulargewicht:
458.51
Formel:
C27H26N2O5
Target-Kategorie:
Akt,Apoptosis,Autophagy,mTOR,PI3K
Anwendungsbeschreibung:
MCE Product type: Reference compound
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