GSK3-IN-10 (Compound 4) is a multi-target inhibitor, that mainly targets GSK3alpha and GSK3beta with IC50 of 1.0 nM and 2.0 nM. GSK3-IN-10 inhibits the activation of beta-catenin, promotes the neuronal survival, and exhibits a protective effect against endoplasmic reticulum stress[1].
Molekulargewicht:
364.35
CAS Nummer:
[844441-56-1]
Formel:
C17H18F2N4O3
Target-Kategorie:
CDK,CDKL,DYRK,GSK-3,JNK,beta-catenin
Anwendungsbeschreibung:
MCE Product type: Reference compound
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