P2Y14R antagonist 3 (Compound A) is a potent and orally active P2Y14R antagonist with an IC50 value of 23.60 nM and a Kd value of 7.26 µM. P2Y14R antagonist 3 can reduce the degree of lung injury in the Lipopolysaccharides (LPS) (HY-D1056)-induced acute lung injury mice. P2Y14R antagonist 3 can be used for inflammatory diseases[1].
Molekulargewicht:
487.51
Formel:
C26H25N5O5
Target-Kategorie:
P2Y Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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