HIF-PHD-IN-4 (Compound 13) is an orally active PHD2 inhibitor with an IC50 of 100 nM. HIF-PHD-IN-4 can effectively enhance the mobilization of hematopoietic stem cells induced by G-CSF in mice at a dose of 2 mg/kg. HIF-PHD-IN-4 is suitable for research in the field of tumor therapy [1].
Molekulargewicht:
379.41
Formel:
C20H21N5O3
Target-Kategorie:
HIF/HIF Prolyl-Hydroxylase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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