WEHI-3773 is an inhibitor of the interaction between VDAC2 and BAK or BAX. WEHI-3773 inhibits BAX-mediated Apoptosis by blocking the VDAC2-mediated recruitment of BAX to mitochondria. Conversely, WEHI-3773 promotes BAK-mediated Apoptosis by limiting the inhibitory sequestration of BAK by VDAC2. WEHI-3773 is promising for research in the field of anti-cancer [1].
Molekulargewicht:
618.69
Reinheit:
99.89
Formel:
C30H22N10O2S2
Target-Kategorie:
Apoptosis,Bcl-2 Family
Anwendungsbeschreibung:
MCE Product type: Natural Products
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