Darlifarnib, CAS [[3065226-39-0]]

Artikelnummer: MCE-HY-172423
Artikelname: Darlifarnib, CAS [[3065226-39-0]]
Artikelnummer: MCE-HY-172423
Hersteller Artikelnummer: HY-172423
Alternativnummer: MCE-HY-172423-1MG, MCE-HY-172423-5MG, MCE-HY-172423-500UG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: KO-2806
Darlifarnib (KO-2806) is an orally active farnesyl transferase inhibitor. Darlifarnib inhibits the mTORC1 signaling pathway, thereby enhancing the anti-angiogenic properties of tyrosine kinase inhibitors. When used in combination with anti-VEGFR tyrosine kinase inhibitors, Darlifarnib promotes renal cell carcinoma tumor regression and inhibits tumor neovascularization. Darlifarnib sensitizes renal cell carcinoma tumors that progress after anti-VEGFR TKI treatment[1].
Molekulargewicht: 468.51
CAS Nummer: [3065226-39-0]
Formel: C29H20N6O
Target-Kategorie: Farnesyl Transferase,mTOR,VEGFR
Anwendungsbeschreibung: MCE Product type: Reference compound