CIM-834 is an orally active and selective inhibitor targeting the coronavirus membrane protein (M protein), which potently blocks viral assembly against SARS-CoV-2 and SARS-CoV. CIM-834 binds to the short form of the M protein (Mshort) in a non-covalent manner, stabilizing Mshort and preventing its conformational switch to the long form (Mlong) required for virion assembly, thereby inhibiting viral particle formation. CIM-834 is promising for research of COVID-19 and other coronavirus infections[1].
Molekulargewicht:
494.68
Reinheit:
98.71
Formel:
C27H42N8O
Target-Kategorie:
SARS-CoV,Virus Protease
Anwendungsbeschreibung:
MCE Product type: Reference compound
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