ABP/PPAR modulator 1 is an orally active FABP and PPAR multiple modulator (IC50s of 0.65 µM and 1.08 µM for FABP1 and FABP4, EC50 s of 9.19 µM, 2.20 µM and 1.58 µM for PPARalpha, PPARgamma and PPARdelta). ABP/PPAR modulator 1 has potent anti-metabolic dysfunction-associated steatohepatitis (MASH) activity. ABP/PPAR modulator 1 dose-dependently ameliorates multiple pathological characteristics of fatty liver in WD + Carbon tetrachloride-induced MASH mice model[1].
Molekulargewicht:
561.67
Formel:
C33H39NO7
Target-Kategorie:
FABP,PPAR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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