FtsZ-IN-12, CAS [[3099249-36-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-173054
Hersteller Artikelnummer:
HY-173054
Alternativnummer:
MCE-HY-173054-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
FtsZ-IN-12 (Compound 16e) is the inhibitor for filamentous temperature-sensitive mutant Z (FtsZ) that promotes the polymerization of FtsZ protein, inhibits its GTPase activity, thereby interfering with bacterial cell division process. FtsZ-IN-12 exhibits boardspectrum antibacterial activity that inhibits B. subtilis ATCC9372, B. pumilus CMCC63202, S. aureus ATCC25923, E. coli BW25113 and A. baumannii ATCC19606 with MIC of 0.062-1 µg/mL. FtsZ-IN-12 inhibits the formation of bacterial biofilms and exhibits a clearing effect on mature biofilms. FtsZ-IN-12 exhibits bactericidal activity without hemolytic toxicity to mammalian red blood cells (15 mg/kg)[1].
Molekulargewicht:
537.48
CAS Nummer:
[3099249-36-9]
Formel:
C28H32IN3
Target-Kategorie:
Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound
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