BRD4 Inhibitor-40, CAS [[2994635-04-8]] Preis auf Anfrage

Artikelnummer: MCE-HY-173062
Artikelname: BRD4 Inhibitor-40, CAS [[2994635-04-8]] Preis auf Anfrage
Artikelnummer: MCE-HY-173062
Hersteller Artikelnummer: HY-173062
Alternativnummer: MCE-HY-173062-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
BRD4 Inhibitor-40 (Compound 23) is the inhibitor for BRD that inhibits BRD4-BD1, BRD4-BD2, BRD2-BD1 and BRD2-BD2 with IC50s of 16.1, 142.18, 29.35 and 302.35 nM, respectively. BRD4 Inhibitor-40 modulates the expression of c-Myc and p21, arrests cell cycle at G1 phase, inhibits Pkd1-null (PN) renal cystic epithelial cells, and blocks the renal cysts formation in Madin-Darby canine kidney and embryonic kidney vesicle models. BRD4 Inhibitor-40 exhibits renal cysts inhibitory activity in mouse models[1].
Molekulargewicht: 484.60
CAS Nummer: [2994635-04-8]
Formel: C27H32N8O
Target-Kategorie: c-Myc,Epigenetic Reader Domain
Anwendungsbeschreibung: MCE Product type: Reference compound