BRD4 Inhibitor-40, CAS [[2994635-04-8]] Preis auf Anfrage
Artikelnummer:
MCE-HY-173062
Hersteller Artikelnummer:
HY-173062
Alternativnummer:
MCE-HY-173062-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
BRD4 Inhibitor-40 (Compound 23) is the inhibitor for BRD that inhibits BRD4-BD1, BRD4-BD2, BRD2-BD1 and BRD2-BD2 with IC50s of 16.1, 142.18, 29.35 and 302.35 nM, respectively. BRD4 Inhibitor-40 modulates the expression of c-Myc and p21, arrests cell cycle at G1 phase, inhibits Pkd1-null (PN) renal cystic epithelial cells, and blocks the renal cysts formation in Madin-Darby canine kidney and embryonic kidney vesicle models. BRD4 Inhibitor-40 exhibits renal cysts inhibitory activity in mouse models[1].
Molekulargewicht:
484.60
CAS Nummer:
[2994635-04-8]
Formel:
C27H32N8O
Target-Kategorie:
c-Myc,Epigenetic Reader Domain
Anwendungsbeschreibung:
MCE Product type: Reference compound
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