OA-Br-1 is an orally active and selective inhibitor of PTP1B with an IC50 value of 7.08 µM. OA-Br-1 induces apoptosis. OA-Br-1 has broad spectrum anti-proliferative activity against cancer cells, and plays an anti-breast cancer role through the PTP1B/PI3K/AKT signaling pathway both in vitro and in vivo[1].
Molekulargewicht:
808.92
Formel:
C43H70BrNO8
Target-Kategorie:
Apoptosis,Phosphatase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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