STING-IN-12 (compound Y2) is an inhibitor of STING. STING-IN-12 inhibits IFNbeta gene expression (IC50=0.75µM) induced by SR717. STING-IN-12 inhibits STING pathway activation induced by the STING agonist SR717 in THP1 cells and MSA-2-induced STING pathway activation in vivo in mice[1].
Molekulargewicht:
358.27
Formel:
C15H13F3N2O5
Target-Kategorie:
STING
Anwendungsbeschreibung:
MCE Product type: Reference compound
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