PROTAC SMARCA2/4 degrader-38 is a degrader SMARCA2/4 PROTAC (DC50: 3.0 nM and 4.0 nM respectively). PROTAC SMARCA2/4 degrader-38 promotes the ubiquitination and degradation of SMARCA2/4. PROTAC SMARCA2/4 degrader-38 blocks the G0/G1 cell cycle and induces apoptosis. PROTAC SMARCA2/4 degrader-38 can be used in acute myeloid leukemia (AML) research. (Pink: SMARCA2/4 ligand, Blue: VHL ligand (HY-112078), Black: linker, Target Protein Ligand-Linker Conjugates (HY-173343))[1].
Molekulargewicht:
773.94
Reinheit:
99.46
CAS Nummer:
[3081688-77-6]
Formel:
C43H47N7O5S
Target-Kategorie:
Apoptosis,Epigenetic Reader Domain,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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