ST6GAL1-IN-1, CAS [[192876-13-4]]

Artikelnummer: MCE-HY-173496
Artikelname: ST6GAL1-IN-1, CAS [[192876-13-4]]
Artikelnummer: MCE-HY-173496
Hersteller Artikelnummer: HY-173496
Alternativnummer: MCE-HY-173496-10MG,MCE-HY-173496-50MG,MCE-HY-173496-100MG,MCE-HY-173496-5MG,MCE-HY-173496-25MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
ST6GAL1-IN-1 is an orally active selective ST6GAL1 inhibitor (IC50 = 20 µM). ST6GAL1-IN-1 exhibits high antimetastatic potential, effectively inhibiting the migration of MDA-MB-231 cells at noncytotoxic concentrations. ST6GAL1-IN-1 can disrupt integrin sialylation in MDA-MB-231 cells. ST6GAL1-IN-1 inhibits tumor angiogenesis and cancer metastasis via the Integrin/VEGFR2-mediated signaling pathway. ST6GAL1-IN-1 effectively suppresses both tumor growth and cancer metastasis on the MDA-MB-231 xenograft model. ST6GAL1-IN-1 can be used for the study of Triple-negative breast cancer (TNBC)[1].
Molekulargewicht: 562.78
Reinheit: 99.22
CAS Nummer: [192876-13-4]
Formel: C35H50N2O4
Target-Kategorie: Akt,Integrin,Sialyltransferase,VEGFR
Anwendungsbeschreibung: MCE Product type: Reference compound