KI-CDK9d-32, CAS [[3054009-82-1]]
Artikelnummer:
MCE-HY-173523
| Artikelname: |
KI-CDK9d-32, CAS [[3054009-82-1]] |
| Artikelnummer: |
MCE-HY-173523 |
| Hersteller Artikelnummer: |
HY-173523 |
| Alternativnummer: |
MCE-HY-173523-50MG,MCE-HY-173523-25MG,MCE-HY-173523-5MG,MCE-HY-173523-10MG,MCE-HY-173523-1MG |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| KI-CDK9d-32 is a highly selective and potent CDK9 PROTAC degrader (DC50: 0.89 nM). KI-CDK9d-32 promotes the ubiquitination and degradation of CDK9. KI-CDK9d-32 inhibits the MYC pathway and disrupts nucleolar homeostasis. KI-CDK9d-32 exhibits anticancer activity against acute lymphoblastic leukemia and pancreatic cancer. (Pink: CDK9 ligand (HY-153718), Blue: E3 ligase CRBN ligand (HY-163233), Black: Linker (HY-W011657), E3 ligase CRBN ligand-linker conjugate (HY-173525))[1]. |
| Molekulargewicht: |
703.83 |
| Reinheit: |
99.0300 |
| CAS Nummer: |
[3054009-82-1] |
| Formel: |
C39H45N9O4 |
| Target-Kategorie: |
CDK,c-Myc,PROTACs |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
