TCIP3 is a bivalent molecular glue with with dual binding to p300/CBP and BCL6. TCIP3 redirects p300 and CBP to activate programmed cell death genes normally repressed by the oncogenic driver, BCL6. TCIP3 can be used for the study of diffuse large B cell lymphomas (DLBCLs). TCIP3 exhibits no toxicity in non-transformed tonsillar lymphocytes or fibroblasts[1].
Molekulargewicht:
1177.74
Reinheit:
99.30
CAS Nummer:
[3067681-36-8]
Formel:
C58H71ClF2N16O7
Target-Kategorie:
BCL6,Histone Acetyltransferase,Molecular Glues
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten