HDAC6-IN-54 (Compound 9m) is a highly selective HDAC6 (histone deacetylase 6) inhibitor with an IC50 value of 0.021 µM. HDAC6-IN-54 blocks the activation of the NLRP3 inflammasome, which alleviates symptoms of NLRP3 inflammasome-related diseases such as acute peritonitis, inflammatory bowel disease, and psoriasis[1].
Molekulargewicht:
406.43
Formel:
C23H20F2N4O
Target-Kategorie:
HDAC,NOD-like Receptor (NLR)
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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