BMS-986449 Preis auf Anfrage

Artikelnummer: MCE-HY-173630
Artikelname: BMS-986449 Preis auf Anfrage
Artikelnummer: MCE-HY-173630
Hersteller Artikelnummer: HY-173630
Alternativnummer: MCE-HY-173630-100MG,MCE-HY-173630-10MG,MCE-HY-173630-25MG,MCE-HY-173630-50MG,MCE-HY-173630-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
BMS-986449 is a CELMoD molecular glue and an IKZF2/IKZF4 degrader. BMS-986449 targets the degradation of transcription factors Helios (IKZF2) and Eos (IKZF4) in regulatory T (Treg) cells. BMS-986449 redirects the E3 ubiquitin ligase Cereblon to induce the degradation of Helios and Eos, reprogramming Treg cells and enhancing antitumor immunity. BMS-986449 is promising for research of advanced solid tumors[1].
Molekulargewicht: 396.41
Formel: C21H21FN4O3
Target-Kategorie: IKZF Family,Molecular Glues
Anwendungsbeschreibung: MCE Product type: Reference compound