Temozolomide-d3 is the deuterium labeled Temozolomide. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects[1][2].
Molekulargewicht:
197.17
Reinheit:
99.87
CAS Nummer:
[208107-14-6]
Formel:
C6H3D3N6O2
Target-Kategorie:
Apoptosis,Autophagy,DNA Alkylator/Crosslinker
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
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