Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. IC50 value: Target: thrombin Dabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory controls. Of note, there is a growing amount of clinical evidence which shows its safety and efficacy. For these reasons, Dabigatran may suppose a revolution in oral anticoagulation. Dabigatran etexilate was rapidly converted to Dabigatran, with peak plasma dabigatran concentrations being attained after approximately 1.5 h, the bioavailability of Dabigatran after p.o. administration of Dabigatran etexilate was 7.2%.
Molekulargewicht:
499.56
Reinheit:
99.02
CAS Nummer:
[429658-95-7]
Formel:
C27H29N7O3
Target-Kategorie:
Thrombin
Anwendungsbeschreibung:
MCE Product type: Reference compound
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