TEAD1/3/4-IN-1 is an orally active inhibitor of TEAD1/3/4. TEAD1/3/4-IN-1 inhibits the YAP/TAZ-TEAD interaction, with its EC50 being 2 nM. TEAD1/3/4-IN-1 has anti-proliferative activity against NCI-H226 cells. TEAD1/3/4-IN-1 can be used in the research of lung squamous cell carcinoma[1].
Molekulargewicht:
407.32
Reinheit:
99.04
CAS Nummer:
[2762619-63-4]
Formel:
C18H13F4N5O2
Target-Kategorie:
YAP
Anwendungsbeschreibung:
MCE Product type: Reference compound
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