Keap1-IN-2, CAS [[3066895-41-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: Keap1-IN-2, CAS [[3066895-41-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-174287
• Hersteller Artikelnummer: HY-174287
• Alternativnummer: MCE-HY-174287-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Keap1-IN-2 (Compound 164) is a KEAP1 inhibitor (IC50: 2 nM). Keap1-IN-2 indirectly activates Nrf2 by inhibiting KEAP1, thereby enhancing the antioxidant capacity of cells. Keap1-IN-2 promotes the accumulation and nuclear translocation of Nrf2 by blocking KEAP1-mediated Nrf2 degradation. Keap1-IN-2 can be used to study diseases associated with oxidative stress, such as inflammatory bowel disease, Crohns disease, and immune diseases such as ulcerative colitis[1].

Produkteigenschaften

• Molekulargewicht: 442.90
• CAS Nummer: [3066895-41-5]
• Formel: C21H23ClN6O3
• Target-Kategorie: Keap1-Nrf2

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound