MT-125 free base is a specific and well-tolerated inhibitor of non-muscle myosin IIA (Ki,NMIIA = 2.7 µM) and IIB (EC50 = 1.7 µM). MT-125 free base can pass through the blood-brain barrier. MT-125 free base induces ferroptosis and DNA damage by increasing the levels of reactive oxygen species (ROS) within tumor cells. MT-125 free base can enhance the PDGFR signaling pathway. MT-125 free base can be used for research on glioblastoma[1].
Molekulargewicht:
357.41
Reinheit:
98.67
CAS Nummer:
[2404652-80-6]
Formel:
C22H19N3O2
Target-Kategorie:
Akt,ERK,Ferroptosis,mTOR,Myosin,PDGFR,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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