RN277 is an inhibitor for LRRK2 type II kinase. RN277 can be used as a cellular tool targeting the LRRK2 inactive state. RN277 can inhibit LRRK1 kinase activity in vitro. RN277 inhibits LRRK2 kinase activity in vitro (IC50 = 70 nM). RN277 reduces phosphorylation of Rab8a dose-dependently. RN277 can be studied in research for Parkingsons disease[1].
Molekulargewicht:
585.10
Formel:
C31H33ClN8O2
Target-Kategorie:
LRRK2
Anwendungsbeschreibung:
MCE Product type: Reference compound
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