PROTAC sEH degrader-2 is a PROTAC targeting degradation agent for soluble epoxide hydrolase (sEH) with pIC50 values of the catalytic domain of 8.37 (human sEH-H) and 7.12 (mouce sEH-H). PROTAC sEH degrader-2 can be used for the research related to inflammation and neuroinflammation, such as Alzheimers disease[1]. (Structure Note: Pink: sEH-H ligand (HY-174225), Blue: CRBN Ligand (HY-103597), Black: linker, E3 + linker (HY-141011))
Molekulargewicht:
1148.14
Formel:
C54H57F4N9O13S
Target-Kategorie:
Epoxide Hydrolase,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
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