PROTAC PI3K/110beta degrader-2, CAS [[3070438-79-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-174469
Hersteller Artikelnummer:
HY-174469
Alternativnummer:
MCE-HY-174469-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
PROTAC PI3K/110beta degrader-2 is a selective PI3K/p110beta PROTAC degrader. PROTAC PI3K/110beta degrader-2 can significantly degrade 110beta protein and inhibit the expression of P-glycoprotein. PROTAC PI3K/110beta degrader-2 can increase the level of reactive oxygen species (ROS). PROTAC PI3K/110beta degrader-2 exerts anti-tumor effects by activating the endoplasmic reticulum stress (ERS)-mediated mitochondrial apoptosis pathway and inhibiting the AKT/Bcl-2 signaling pathway. PROTAC PI3K/110beta degrader-2 can be used for research on cancer. (Pink: PI3K/110beta Ligand (HY-75124), Blue: VHL Ligand (HY-125845), Black: Linker (HY-W002042))[1].
Molekulargewicht:
948.18
CAS Nummer:
[3070438-79-5]
Formel:
C51H65N9O7S
Target-Kategorie:
Akt,Apoptosis,Bcl-2 Family,Na+/K+ ATPase,P-glycoprotein,PI3K,PROTACs,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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