TRPM8 antagonist 4, CAS [[3107363-68-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-174825
Hersteller Artikelnummer:
HY-174825
Alternativnummer:
MCE-HY-174825-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
TRPM8 antagonist 4 is a CB2R partial agonist (EC50=54.2 nM, Ki=3.2 µM) and TRPM8 antagonists (IC50=42.3 nM) with high functional selectivity and good physicochemical properties. TRPM8 antagonist 4 has significant anti-inflammatory and analgesic effects and good safety, reduces the mRNA expression of TNF-alpha, IL-6, and IL-1beta[1].
