BT-O2C, CAS [[3055107-34-8]] Preis auf Anfrage

Artikelnummer: MCE-HY-174866
Artikelname: BT-O2C, CAS [[3055107-34-8]] Preis auf Anfrage
Artikelnummer: MCE-HY-174866
Hersteller Artikelnummer: HY-174866
Alternativnummer: MCE-HY-174866-5MG,MCE-HY-174866-50MG,MCE-HY-174866-10MG,MCE-HY-174866-25MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
BT-O2C is a highly selective p300 PROTAC degrader. BT-O2C can significantly degrade the level of p300 in HAP1 cells. BT-O2C has significant cytotoxicity in CIC:DUX4 sarcoma (CDS) cell lines (IC50 ranges from 152 to 221 nM) and significantly reduces the expression of CDS target genes (ETV1, ETV4, ETV5). BT-O2C can be used for research on cancer. (Pink: p300 Ligand (HY-174868), Blue: CRBN Ligand (HY-W023573), Black: Linker, CRBN Ligand+Linker (HY-174869))[1].
Molekulargewicht: 973.94
CAS Nummer: [3055107-34-8]
Formel: C48H48F5N9O8
Target-Kategorie: Epigenetic Reader Domain,Histone Acetyltransferase,PROTACs
Anwendungsbeschreibung: MCE Product type: Reference compound